Otis Rush (born April 29, 1934 in Philadelphia, Mississippi) is a blues musician, singer and guitarist. His distinctive guitar style features a slow burning sound, jazz-style arpeggios and long bent notes. With similar qualities to Luther Allison, Magic Sam, Buddy Guy and Albert King, his sound became known as West Side Chicago blues and became an influence on Michael Bloomfield, Eric Clapton, Peter Green and Stevie Ray Vaughan.
Rush is left-handed and, unlike many left-handed guitarists, plays a right-handed instrument upside-down without restringing it. It is widely believed that this contributes to his distinctive sound. Other guitarists who use this method include Albert King, Dick Dale, Doyle Bramhall II, Coco Montoya and Lefty Dizz. He has a wide-ranging, powerful tenor voice.